Our experts at GRC have the cleaning validation knowledge and
experience to design a specific cleaning regime tailored to your
requirements, or to perform a clean on an already constructed
system to identify any particular areas of poor cleaning such as
pipe drops/elbows, additive lines.
AREAS OF EXPERTISE
SIP
-
Use of Kaye Validator to ensure pipework and contact
surfaces achieve sterility and sanitisation.
- Report construction to graphically and statistically represent
data.
- Identification of any specific cold spots/lag areas.
- UV/Riboflavin testing to confirm effective cleaning of all
areas eg Fermenter vessels.
CIP
- Product Recovery
- Multidirectional stationary sprays v 360° rotation
- Once through v recirculation of cleaning agents
- Intensity of cleaning regime
- Number of steps
- Automated v Manual cleaning
Swabbing
- Identification of difficult to clean/reach areas
- Provides level of contamination risk
- Identifies any areas of potential buildup which may result in
pathogens
Rinse Water Testing
- Bioburden
- Total Organic Carbon
- Endotoxin
- Conductivity
- pH
- Nitrates
